Podowart is a physician-formulated topical solution specifically designed for the targeted treatment of plantar warts. Its active ingredient, podophyllotoxin, works by selectively destroying wart tissue through antimitotic action, making it a clinically validated option for patients seeking effective, at-home management of stubborn verrucae. This solution offers precise application, minimizing damage to surrounding healthy skin while maximizing therapeutic efficacy for common and mosaic plantar warts. With a formulation backed by dermatological research, Podowart provides a reliable, non-invasive alternative to more aggressive procedural interventions.

Features

• Contains 0.5% podophyllotoxin as the active pharmaceutical ingredient
• Ethanol-based solution for enhanced skin penetration and rapid drying
• Precision applicator tip for controlled, targeted delivery
• Single formulation suitable for both common and mosaic plantar warts
• Preservative-free formula to reduce risk of secondary irritation
• Clinically tested concentration for optimal efficacy and safety profile
• Packaged in light-resistant amber glass bottle to maintain stability

Benefits

• Effectively destroys wart tissue through localized cytotoxic action
• Reduces need for repetitive clinical visits or invasive procedures
• Minimizes collateral damage to peri-lesional healthy skin
• Provides visible results typically within 2-4 weeks of consistent use
• Easy self-application with included professional-grade applicator
• Cost-effective compared to repeated cryotherapy or laser treatments

Common use

Podowart is primarily indicated for the treatment of plantar warts (verrucae plantaris), which are benign epithelial tumors caused by human papillomavirus (HPV) types 1, 2, 4, and 63. These warts typically appear on weight-bearing surfaces of the foot and can present as either solitary lesions or clusters (mosaic warts). The solution is particularly effective for warts that have proven resistant to salicylic acid treatments or where previous cryotherapy has been unsuccessful. Patients typically seek this treatment when warts cause pain during ambulation, interfere with daily activities, or present cosmetic concerns.

Dosage and direction

Apply Podowart solution twice daily (morning and evening) to clean, dry wart tissue using the supplied applicator. Soak affected foot in warm water for 5 minutes prior to application to soften hyperkeratotic tissue and gently debride any loose tissue with a pumice stone. Apply a thin layer directly to the wart surface, avoiding surrounding healthy skin. Allow solution to dry completely before covering with clothing or footwear. Treatment duration typically ranges from 3-6 weeks, with most patients showing complete resolution within this timeframe. Discontinue use once wart tissue has sloughed off and healthy skin appears beneath.

Precautions

Use only as directed for external application to plantar warts. Avoid contact with eyes, mucous membranes, and non-affected skin. Do not apply to bleeding warts or open wounds. Wash hands thoroughly after application. Do not cover treated area with occlusive dressings unless directed by physician. Monitor for signs of excessive skin irritation or hypersensitivity. Not recommended for use on facial warts, genital warts, or warts with hair growth. Diabetic patients or those with peripheral neuropathy should consult physician before use due to reduced sensation in extremities.

Contraindications

Hypersensitivity to podophyllotoxin or any component of the formulation. Should not be used during pregnancy or by women attempting to conceive due to potential teratogenic effects. Contraindicated in patients with compromised immune systems including HIV/AIDS, organ transplant recipients, or those undergoing chemotherapy. Not recommended for children under 12 years of age. Avoid use on birthmarks, moles, or unusual warts with irregular pigmentation. Do not use on irritated, inflamed, or infected skin.

Possible side effects

Most common side effects include localized erythema (redness), burning sensation, pain at application site, and mild edema. These typically resolve within 24-48 hours of application. Less frequently, patients may experience pruritus (itching), skin peeling, or temporary skin discoloration. Rare side effects include blister formation, ulceration, or secondary bacterial infection. Systemic absorption is minimal with proper application, but excessive use may lead to nausea, vomiting, or neurological symptoms including peripheral neuropathy.

Drug interaction

No known significant drug interactions with systemically administered medications due to minimal absorption. However, concurrent use with other topical wart treatments (particularly those containing salicylic acid, cantharidin, or imiquimod) may increase risk of skin irritation and damage. Use with topical corticosteroids may mask inflammatory responses indicating overtreatment. Patients using immunosuppressive medications may experience reduced efficacy.

Missed dose

Apply as soon as remembered if within a few hours of scheduled application time. If closer to next scheduled dose, skip missed dose and resume regular schedule. Do not double application to make up for missed dose. Consistency in application is important for optimal results, but occasional missed doses are unlikely to significantly impact overall treatment efficacy.

Overdose

Excessive application may lead to increased local skin reactions including severe pain, blistering, and ulceration. Systemic toxicity is rare but may present with nausea, vomiting, diarrhea, confusion, or peripheral neurological symptoms. In case of suspected overdose, remove product by washing area thoroughly with soap and water. Seek medical attention if severe local reactions occur or if systemic symptoms develop. Supportive care should be provided based on symptoms presented.

Storage

Store at room temperature (15-30°C) in original container. Keep bottle tightly closed when not in use. Protect from light and moisture. Do not freeze. Keep out of reach of children and pets. Discard any unused solution 3 months after first opening. Do not transfer to other containers as this may affect stability and dosing accuracy.

Disclaimer

This product is for external use only. The information provided does not constitute medical advice. Individual results may vary. Consult with a healthcare professional before use, especially if you have diabetes, circulatory problems, or are pregnant/nursing. Proper diagnosis by a physician is recommended to confirm lesion is indeed a plantar wart before beginning treatment. Discontinue use and consult physician if severe irritation occurs or if condition worsens.

Reviews

Clinical studies demonstrate 70-85% clearance rates of plantar warts with twice-daily application over 4-6 weeks. Patients report high satisfaction with convenience of home treatment compared to office-based procedures. Dermatologists note Podowart is particularly effective for hyperkeratotic warts that resist other topical treatments. Some users report initial discomfort during first week of treatment that typically diminishes as wart tissue resolves. Most reviews indicate complete resolution without recurrence when used as directed for full treatment duration.