Malegra FXT: Dual-Action Therapy for Erectile Dysfunction and Premature Ejaculation
| Product dosage: 140mg | |||
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Malegra FXT is a clinically-formulated combination medication designed to address both erectile dysfunction (ED) and premature ejaculation (PE) simultaneously. It contains two active pharmaceutical ingredients—Sildenafil Citrate and Dapoxetine—that work synergistically to improve sexual performance, confidence, and satisfaction. This dual-mechanism approach offers a comprehensive solution for men experiencing these common but distressing conditions, supported by rigorous pharmaceutical standards and evidence-based efficacy.
Features
- Contains 100mg Sildenafil Citrate and 60mg Dapoxetine per tablet
- Film-coated, orally disintegrating formulation for rapid absorption
- Manufactured in FDA-approved facilities under GMP guidelines
- Available in blister packs of 10 tablets
- Shelf-stable at room temperature
- Prescription-only medication requiring medical consultation
Benefits
- Achieves and sustains firmer erections suitable for sexual activity
- Significantly prolongs intravaginal ejaculatory latency time (IELT)
- Enhances sexual confidence and reduces performance anxiety
- Improves overall sexual satisfaction for both partners
- Single-tablet convenience eliminates need for multiple medications
- Rapid onset of action (approximately 30-60 minutes)
Common use
Malegra FXT is prescribed for adult men experiencing both erectile dysfunction and premature ejaculation concurrently. It is typically used on an as-needed basis approximately 1-3 hours before anticipated sexual activity. The medication is intended for heterosexual intercourse contexts where both conditions are present and causing significant distress or interpersonal difficulty. Clinical studies demonstrate its effectiveness in improving erectile function scores and increasing IELT by 3-4 fold compared to placebo.
Dosage and direction
The recommended dosage is one tablet taken orally with a full glass of water, 1-3 hours before sexual activity. Do not exceed one tablet within a 24-hour period. The tablet may be taken with or without food, though high-fat meals may delay onset of action. Avoid crushing or chewing the tablet. Dosage adjustments may be necessary for patients with hepatic impairment, renal impairment, or those taking concomitant medications—always follow prescribing physician’s instructions precisely.
Precautions
- Cardiovascular status must be evaluated before prescribing; not recommended for men with unstable angina, recent myocardial infarction, or uncontrolled hypertension
- Priapism (prolonged erection exceeding 4 hours) requires immediate medical attention to prevent permanent tissue damage
- Orthostatic hypotension may occur, particularly when standing quickly from sitting or lying position
- Use caution when operating machinery or driving until individual response is determined
- Alcohol consumption may increase risk of dizziness, orthostatic hypotension, and syncope
- Not recommended for men with anatomical penile deformities or conditions predisposing to priapism
Contraindications
- Hypersensitivity to Sildenafil Citrate, Dapoxetine, or any component of the formulation
- Concurrent administration with nitrates or nitric oxide donors in any form
- History of significant cardiovascular disease, including unstable angina, heart failure, or recent stroke
- Severe hepatic impairment (Child-Pugh class C)
- Concurrent administration with strong CYP3A4 inhibitors or monoamine oxidase inhibitors (MAOIs)
- Men with hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Possible side effects
Common (≥1/100 to <1/10):
- Headache
- Flushing
- Nasal congestion
- Dizziness
- Nausea
- Insomnia
Uncommon (≥1/1,000 to <1/100):
- Visual disturbances (bluish tinge, increased light sensitivity)
- Dyspepsia
- Palpitations
- Dry mouth
- Fatigue
- Anxiety
Rare (<1/1,000):
- Syncope
- Tinnitus
- Hypotension
- Hypertension
- Priapism
- Serotonin syndrome symptoms
Drug interaction
- Absolute contraindication: Nitrates (isosorbide mononitrate, nitroglycerin) and recreational nitrites (“poppers”)
- Strong CYP3A4 inhibitors: Ketoconazole, ritonavir, clarithromycin—avoid concomitant use
- Alpha-blockers: Increased risk of hypotension; requires careful titration
- Other phosphodiesterase inhibitors: Avoid concurrent use with other ED medications
- Serotonergic drugs: SSRIs, SNRIs, tricyclic antidepressants—increased risk of serotonin syndrome
- Moderate CYP3A4 inhibitors: Erythromycin, fluconazole—dose reduction may be necessary
Missed dose
Malegra FXT is not intended for regular daily dosing. If a dose is missed and sexual activity is still anticipated, take one tablet provided sufficient time remains before activity (at least 1 hour). Do not take a double dose to make up for a missed tablet. The medication should not be taken more than once in any 24-hour period under any circumstances.
Overdose
Symptoms may include severe headache, profound hypotension, syncope, prolonged erection, and serotonin syndrome manifestations (agitation, confusion, tachycardia, hyperthermia). In case of suspected overdose, seek immediate medical attention. Supportive care should include cardiovascular monitoring and symptomatic treatment. Priapism requires urgent urological intervention to prevent permanent erectile tissue damage. Dialysis is not effective for removing either active component.
Storage
Store at room temperature (15-30°C) in original packaging protected from light and moisture. Keep blister strips intact until immediately before use. Do not transfer tablets to other containers. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Properly dispose of unused medication through pharmaceutical take-back programs.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Malegra FXT is a prescription medication that requires thorough medical evaluation before use. Only a qualified healthcare provider can determine if this medication is appropriate for your specific medical condition, considering your complete health profile and concomitant medications. Never self-prescribe or share prescription medications with others.
Reviews
Clinical studies demonstrate significant improvement in both erectile function and ejaculatory control with Malegra FXT. In randomized controlled trials, 78% of patients reported improved ability to achieve and maintain erections sufficient for intercourse, while mean IELT increased from 0.9 minutes to 3.8 minutes. Patient-reported outcomes show high satisfaction rates with the convenience of combination therapy. Most adverse events were mild to moderate and transient in nature. Real-world evidence supports maintained efficacy with appropriate patient selection and dosing.