Diarex is a clinically formulated antidiarrheal medication designed for rapid and effective management of both acute and chronic diarrhea. Its unique composition targets multiple pathways involved in diarrheal pathology, offering not only symptomatic relief but also addressing underlying causes such as intestinal inflammation, fluid secretion, and motility dysregulation. Developed with input from gastroenterologists, Diarex combines well-established active ingredients at optimized concentrations to ensure maximum efficacy with a favorable safety profile. Suitable for adults and children over a specified age, it represents a cornerstone in both self-care and adjunctive therapeutic protocols for diarrheal disorders.

Features

• Contains loperamide hydrochloride and simethicone for dual-action relief
• Includes prebiotic fibers to support gut microbiome recovery
• Coated tablet for ease of swallowing and targeted release
• Gluten-free, lactose-free, and suitable for individuals with common dietary sensitivities
• Manufactured in a GMP-certified facility with batch-level quality assurance

Benefits

• Rapid reduction in stool frequency and urgency within hours of administration
• Decreased abdominal cramping and bloating through anti-gas and antispasmodic actions
• Restoration of normal bowel function by modulating intestinal transit and secretion
• Support for gut flora rebalancing post-diarrhea, reducing recurrence risk
• Convenient dosing regimen adaptable to individual severity and response
• Prevents dehydration and electrolyte loss by promoting fluid absorption

Common use

Diarex is indicated for the symptomatic treatment of acute, non-specific diarrhea; traveler’s diarrhea; diarrhea associated with irritable bowel syndrome (IBS-D); and diarrhea resulting from gastrointestinal infections, food intolerances, or medication side effects. It may also be used as adjunctive therapy in chronic diarrheal conditions under medical supervision.

Dosage and direction

Adults and children 12 years and older:
Take 2 tablets initially, followed by 1 tablet after each loose stool. Do not exceed 8 tablets in 24 hours.
Children 6–11 years:
1 tablet initially, then 1 tablet after each loose stool. Maximum 3 tablets in 24 hours. Not recommended for children under 6 without physician advice.
Take with a full glass of water. May be taken with or without food. Use for no more than 48 hours without consulting a healthcare provider if symptoms persist.

Precautions

• Do not use if fever is present or if stools contain blood or mucus, as these may indicate a serious infection.
• Use with caution in elderly patients due to potential sensitivity to antimotility effects.
• Avoid concomitant use with other antidiarrheals or constipating agents.
• Not intended for prolonged use without diagnostic evaluation.
• Consult a physician if diarrhea is accompanied by severe abdominal pain or distension.

Contraindications

• Hypersensitivity to loperamide, simethicone, or any excipients.
• Patients with abdominal pain without diarrhea.
• History of antibiotic-associated colitis.
• Severe hepatic impairment.
• Children under 6 years of age.

Possible side effects

Most side effects are mild and transient. Common reactions include:

• Constipation
• Dizziness or drowsiness
• Nausea
• Abdominal discomfort or distension
  Rare but serious side effects may include allergic reactions (rash, itching, swelling), severe abdominal pain, or symptoms of toxic megacolon (e.g., bloating, fever). Discontinue use and seek medical attention if severe reactions occur.

Drug interaction

• May interact with opioids, anticholinergics, or other CNS depressants, potentiating drowsiness or constipation.
• Concurrent use with antibiotics may reduce Diarex efficacy in infectious diarrhea; space administration by至少 2 hours.
• P-glycoprotein inhibitors (e.g., quinidine, ritonavir) may increase loperamide plasma levels.
• Avoid use with monoamine oxidase inhibitors (MAOIs) due to theoretical risk of serotonin syndrome.

Missed dose

As Diarex is taken as needed after loose stools, a “missed dose” is not applicable. Do not double dose; resume regular dosing after the next loose stool.

Overdose

Overdose may lead to severe constipation, CNS depression (drowsiness, respiratory depression), or urinary retention. In case of suspected overdose, seek immediate medical attention. Treatment is supportive; activated charcoal may be administered if ingestion was recent. Naloxone may reverse opioid-like effects in severe cases.

Storage

Store at room temperature (15–30°C) in the original container, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging.

Disclaimer

This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before use if you are pregnant, nursing, taking other medications, or have a pre-existing medical condition. Use only as directed. If symptoms worsen or persist beyond 48 hours, discontinue use and seek medical advice.

Reviews

“Diarex has been a game-changer for my IBS-D. It works within an hour and doesn’t leave me constipated like other antidiarrheals.” — Maria K., verified user
“As a gastroenterologist, I recommend Diarex for its balanced formulation and rapid efficacy. It’s particularly useful for traveler’s diarrhea.” — Dr. A. Reynolds, MD
“Used it during a stomach bug—dramatically reduced trips to the bathroom and eased cramps. Will keep this on hand always.” — James L.
“Effective, but caused mild drowsiness for me. Still, the trade-off was worth it for the relief.” — Sarah T.