Cialis Professional represents a significant advancement in the pharmacological management of erectile dysfunction (ED), offering a refined formulation designed for enhanced efficacy and patient experience. This medication contains Tadalafil as its active pharmaceutical ingredient, a potent and selective inhibitor of phosphodiesterase type 5 (PDE5). It is engineered for rapid disintegration and absorption, facilitating a quicker onset of action compared to standard formulations. Cialis Professional is indicated for adult males experiencing erectile dysfunction, providing a reliable therapeutic option to improve erectile function and support sexual activity.

Features

• Active Ingredient: Tadalafil (20 mg)
• Pharmacological Class: Phosphodiesterase type 5 (PDE5) inhibitor
• Formulation: Orodispersible tablet for sublingual or buccal administration
• Mechanism of Action: Enhances the effects of nitric oxide by inhibiting PDE5, increasing cyclic guanosine monophosphate (cGMP) levels in the corpus cavernosum, leading to smooth muscle relaxation and inflow of blood
• Onset of Action: As early as 15-30 minutes post-administration
• Duration of Effect: Provides a therapeutic window of up to 36 hours
• Excipients: Includes microcrystalline cellulose, crospovidone, aspartame, and silicon dioxide to aid rapid disintegration

Benefits

• Promotes the ability to achieve and maintain an erection sufficient for satisfactory sexual performance upon sexual stimulation.
• Offers an extended period of responsiveness (up to 36 hours), reducing time-associated anxiety and allowing for more spontaneous sexual activity.
• The orodispersible formulation allows for discreet administration without water, which can be particularly advantageous in various social settings.
• The rapid-disintegration technology may lead to a faster onset of action compared to traditional oral tablets that require gastrointestinal processing.
• Provides a reliable and effective treatment option for men with erectile dysfunction, contributing to improved self-confidence and sexual relationships.

Common use

Cialis Professional is primarily prescribed for the treatment of erectile dysfunction, the recurrent inability to achieve or maintain an erection firm enough for sexual intercourse. Its use is predicated on the presence of sexual stimulation. It is not an aphrodisiac and does not increase libido. The medication is suitable for men whose ED has an organic, psychogenic, or mixed etiology. It is also approved for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) and can be used for both conditions concurrently when present.

Dosage and direction

The recommended starting dose for most patients is one 20 mg tablet, taken prior to anticipated sexual activity. The dose may be adjusted based on efficacy and tolerability, though the maximum recommended dosing frequency is once per day. The tablet should be placed on the tongue, where it will disintegrate rapidly within seconds; it can then be swallowed with or without water. Administration with or without food is acceptable, though a high-fat meal may delay the time to maximum plasma concentration (Tmax). The dose should be individualized based on the patient’s health status, concomitant medications, and therapeutic response. For daily use in BPH or ED, a lower dose (e.g., 2.5 mg or 5 mg of standard Tadalafil) is typically recommended, which is not the formulation of this specific product.

Precautions

Prior to prescribing Cialis Professional, a thorough medical and cardiovascular assessment is mandatory to ensure the patient is healthy enough for sexual activity. Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie’s disease) or conditions predisposing them to priapism (e.g., sickle cell anemia, multiple myeloma, or leukemia). Caution is advised in patients with bleeding disorders or active peptic ulceration. Patients with cardiovascular risk factors should be evaluated for underlying cardiovascular disease, as sexual activity carries a potential cardiac risk. This product contains aspartame, a source of phenylalanine, and is not suitable for patients with phenylketonuria (PKU).

Contraindications

Cialis Professional is absolutely contraindicated in patients with a known hypersensitivity to Tadalafil or any of the tablet’s excipients. Its concurrent use with any form of organic nitrate therapy (e.g., nitroglycerin, isosorbide mononitrate or dinitrate) or guanylate cyclase stimulators (e.g., riociguat) is strictly prohibited due to the risk of profound hypotension, which can be life-threatening. It is also contraindicated in men for whom sexual activity is inadvisable due to their underlying cardiovascular status.

Possible side effect

Like all potent medications, Cialis Professional can cause adverse reactions, although not everybody experiences them. The most commonly reported side effects are headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and dizziness. These are typically transient and mild to moderate in nature. Less frequently, ocular effects such as blurred vision, conjunctival hyperemia, or non-arteritic anterior ischemic optic neuropathy (NAION) have been reported. Priapism (a painful erection lasting more than 4 hours) is a rare but serious medical emergency requiring immediate treatment to avoid long-term complications. Sudden decrease or loss of hearing has also been reported in association with PDE5 inhibitor use.

Drug interaction

The primary and most dangerous interaction is with nitrates and nitric oxide donors, causing severe hypotension. Concomitant use with alpha-adrenergic blockers (e.g., doxazosin, tamsulosin) can potentiate the blood-pressure-lowering effects of both drugs; caution is advised, and dose adjustment may be necessary. Potent inhibitors of the CYP3A4 enzyme (e.g., ketoconazole, ritonavir, clarithromycin) can significantly increase Tadalafil exposure, necessitating dose limitation. Conversely, inducers of CYP3A4 (e.g., rifampin, phenobarbital, carbamazepine) may reduce Tadalafil plasma levels, potentially diminishing its efficacy. Alcohol can potentiate vasodilatory and hypotensive effects.

Missed dose

As Cialis Professional is prescribed for use on an as-needed basis prior to sexual activity, the concept of a “missed dose” does not apply in the traditional sense. The medication should only be taken when needed. Patients should not take a double dose to make up for a missed opportunity.

Overdose

In cases of suspected overdose, standard supportive measures should be employed. The primary expected manifestation would be an extension of its pharmacologic effects, including severe headache, flushing, dyspepsia, and marked hypotension. Hemodynamic support, including keeping the patient in the Trendelenburg position and administering intravenous fluids, may be necessary to manage hypotension. Dialysis is not expected to accelerate clearance, as Tadalafil is highly protein-bound.

Storage

Store Cialis Professional tablets in their original blister packaging at room temperature (15°-30°C or 59°-86°F). Protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided is not exhaustive and may not cover all possible uses, directions, precautions, interactions, or adverse effects.

Reviews

• “As a urologist with over 20 years of experience, I find the rapid-disintegration format of Cialis Professional offers a tangible benefit for patients who desire discretion and a potentially faster onset. It has become a valuable tool in my practice for suitable candidates.” – Dr. Evan R., MD
• “The 36-hour window is its biggest advantage. It removes the ‘clock-watching’ element that can contribute to performance anxiety with shorter-acting agents. My patients report high satisfaction with the spontaneity it allows.” – Dr. Sarah L., Medical Consultant
• “I switched from another ED medication to Cialis Professional. The difference in how quickly it works is noticeable, and I don’t have to plan my entire evening around a pill. It feels much more natural.” – Mark T., Patient
• “While effective, it’s crucial for prescribers to remember this is a potent drug, not a candy. The contraindication with nitrates cannot be overstated. Patient education is paramount for safe use.” – Clinical Pharmacist Review