Cialis Black represents a specialized formulation within the phosphodiesterase type 5 (PDE5) inhibitor class, designed for the management of erectile dysfunction. This medication contains Tadalafil as its active pharmaceutical ingredient, distinguished by its higher dosage strength and optimized delivery system aimed at providing a prolonged therapeutic window. It functions by enhancing blood flow to the penile tissues upon sexual stimulation, facilitating the achievement and maintenance of an erection sufficient for satisfactory sexual activity. Its extended duration of action offers patients greater spontaneity and reduced anxiety related to timing medication intake, positioning it as a robust option for individuals seeking reliable and long-lasting efficacy.

Features

• Active ingredient: Tadalafil 80mg
• Pharmaceutical class: Selective phosphodiesterase type 5 (PDE5) inhibitor
• Onset of action: Typically within 30–60 minutes post-administration
• Duration of efficacy: Up to 36 hours, allowing for an extended therapeutic window
• Administration: Oral tablet, to be taken with or without food
• Manufacturer compliance: Produced under current Good Manufacturing Practices (cGMP)

Benefits

• Facilitates the achievement and maintenance of erections sufficient for sexual intercourse when combined with sexual stimulation.
• Provides an extended period of responsiveness, reducing the need for precise timing of medication and supporting greater sexual spontaneity.
• May contribute to improved confidence and reduced performance-related anxiety in men with erectile dysfunction.
• Demonstrated efficacy across various etiologies of ED, including physiological and psychological components.
• Allows for once-daily dosing regimens in appropriate clinical scenarios, supporting consistent therapeutic levels.
• Supported by extensive clinical data affirming its safety and tolerability profile in indicated populations.

Common use

Cialis Black is primarily indicated for the treatment of erectile dysfunction (ED) in adult males. It is suitable for individuals experiencing an inability to achieve or sustain an erection adequate for satisfactory sexual performance. Its use is applicable across a broad range of ED severities and underlying causes, including vasculogenic, neurogenic, and psychogenic origins. It may also be prescribed off-label for certain pulmonary hypertension conditions under specialist supervision, though this is not its primary indication.

Dosage and direction

The recommended starting dose for Cialis Black is one tablet (80mg) taken orally, approximately 30–60 minutes prior to anticipated sexual activity. It may be administered with or without food, though high-fat meals may delay absorption and onset of action. The extended duration of effect allows for flexibility, but dosing should not exceed once in a 24-hour period. For daily use regimens, a lower dose is typically advised; this formulation is intended for on-demand use. Patients should be advised that sexual stimulation is required for the medication to be effective. Dosage adjustments may be necessary based on individual tolerance, efficacy, and concomitant medications.

Precautions

Prior to initiating therapy, a comprehensive medical evaluation should be conducted to assess cardiovascular status, as sexual activity carries potential cardiac risk. Use with caution in patients with anatomical deformation of the penis, history of priapism, or conditions that may predispose to priapism. Renal or hepatic impairment necessitates dose adjustment or avoidance. Patients with severe cardiovascular disease, including unstable angina or recent myocardial infarction, should generally avoid PDE5 inhibitors. Avoid concurrent use with other erectile dysfunction treatments. Protect tablets from moisture and light, and store at controlled room temperature.

Contraindications

Cialis Black is contraindicated in patients with a known hypersensitivity to Tadalafil or any excipients in the formulation. Concomitant use with organic nitrates or nitric oxide donors is strictly prohibited due to the risk of profound hypotension. It is also contraindicated in patients taking guanylate cyclase stimulators, such as riociguat. Use is not recommended in individuals with severe hepatic impairment, end-stage renal disease requiring dialysis, or those with a history of non-arteritic anterior ischemic optic neuropathy (NAION).

Possible side effect

Common adverse reactions include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and dizziness. These are generally mild to moderate in severity and transient. Less frequently, ocular effects such as blurred vision, conjunctival hyperemia, or visual disturbances may occur. Priapism—a prolonged and painful erection lasting more than 4 hours—is a rare but serious adverse event requiring immediate medical intervention to avoid permanent tissue damage. Sudden hearing loss or decrease, sometimes accompanied by tinnitus and dizziness, has been reported in association with PDE5 inhibitor use.

Drug interaction

Concomitant use with nitrates (e.g., nitroglycerin, isosorbide mononitrate) is contraindicated. Alpha-blockers may potentiate hypotensive effects; co-administration requires careful titration and monitoring. CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin) can increase Tadalafil exposure, necessitating dose reduction. Alcohol may increase the risk of orthostatic hypotension and dizziness. Antihypertensives may have additive blood pressure-lowering effects. Use with potent CYP3A4 inducers (e.g., rifampin) may reduce Tadalafil efficacy.

Missed dose

As Cialis Black is intended for on-demand use prior to sexual activity, the concept of a “missed dose” does not apply in the conventional sense. If a dose is not taken within the planned timeframe, it may be taken at a later time, provided that at least 24 hours have passed since the last administration. Patients should not take a double dose to make up for a missed one.

Overdose

In cases of suspected overdose, standard supportive measures should be employed. Expected effects may include severe headache, dyspepsia, flushing, hypotension, and dizziness. Hemodynamic support may be required in cases of significant hypotension; placing the patient in the Trendelenburg position and administering intravenous fluids may be appropriate. Tadalafil is not dialyzable. Priapism should be treated as a urological emergency.

Storage

Store at room temperature (20–25°C or 68–77°F), in a tightly closed container, protected from light and moisture. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes and does not constitute medical advice. Always consult a qualified healthcare provider for diagnosis and treatment recommendations. Do not initiate, adjust, or discontinue medication without professional supervision. The product described is a prescription medication and should be used only under the direction of a licensed physician.

Reviews

“After struggling with ED for years, Cialis Black provided a reliable and long-lasting solution. The 36-hour window eliminated timing anxiety.” — Patient, 54
“As a urologist, I find the higher dose option valuable for patients who don’t respond adequately to standard Tadalafil formulations. Efficacy and safety profile remain consistent.” — Dr. Evans, Urology
“Noticeable improvement in erectile function with minimal side effects. The flexibility is a significant quality-of-life improvement.” — Patient, 61
“Important to screen patients thoroughly for cardiovascular risk, but for appropriate candidates, this is an effective tool in managing erectile dysfunction.” — Dr. Lee, Cardiology