Asthalin (salbutamol sulfate) is a rapid-onset, short-acting beta-2 adrenergic agonist (SABA) bronchodilator indicated for the treatment and prevention of bronchospasm in patients with reversible obstructive airway disease, including asthma and chronic obstructive pulmonary disease (COPD). Delivered via pressurized metered-dose inhaler (pMDI), it works by selectively relaxing smooth muscle in the airways, providing quick symptomatic relief during acute episodes. Its well-established efficacy and safety profile make it a cornerstone in emergency and maintenance respiratory therapy protocols worldwide.

Features

• Contains salbutamol sulfate 100 mcg per actuation
• Delivered via hydrofluoroalkane (HFA) propellant, CFC-free
• Rapid onset of action, typically within 5 minutes
• Duration of effect: 4 to 6 hours
• Portable, pocket-sized inhaler design
• Dose counter for accurate remaining dose tracking
• Compatible with valved holding chambers (spacers) for improved lung deposition

Benefits

• Provides rapid relief from acute asthma attacks and exercise-induced bronchospasm
• Helps restore normal breathing function within minutes of administration
• Reduces the frequency and severity of bronchospastic episodes
• Enables patients to maintain physical activity and quality of life
• May be used as a preventive measure before allergen exposure or exercise
• Trusted by healthcare professionals for emergency respiratory management

Common use

Asthalin is primarily prescribed for the management of reversible obstructive airway conditions. Its most frequent applications include treatment of acute asthma exacerbations, prevention of exercise-induced bronchospasm, and symptomatic relief in COPD patients experiencing bronchospasm. It serves as a rescue medication in asthma action plans and is often used in conjunction with inhaled corticosteroids for comprehensive asthma management. Clinical guidelines recommend it as first-line therapy for immediate relief of bronchoconstriction symptoms.

Dosage and direction

For relief of acute bronchospasm: Adults and children ≥4 years: 1-2 inhalations every 4-6 hours as needed. Maximum recommended dose: 8 inhalations in 24 hours. For prevention of exercise-induced bronchospasm: 2 inhalations 15-30 minutes before exercise. Shake well before use. Prime the inhaler before first use or if not used for more than 2 weeks by releasing 4 test sprays into the air away from the face. Hold inhaler upright with mouthpiece toward patient. Exhale fully, place mouthpiece between lips, and inhale deeply while pressing down firmly on canister. Hold breath for 10 seconds if possible, then exhale slowly. Wait at least one minute between inhalations if more than one puff is prescribed.

Precautions

Use with caution in patients with cardiovascular disorders (especially coronary insufficiency, cardiac arrhythmias, and hypertension), diabetes mellitus, hyperthyroidism, or convulsive disorders. Monitor serum potassium levels as hypokalemia may occur. Paradoxical bronchospasm may occur; if this happens, discontinue immediately and institute alternative therapy. Excessive use may lead to loss of effectiveness and potentially fatal bronchospasm. Not recommended as the sole therapy for severe or unstable asthma. Patients using more than 8 inhalations per day should seek medical advice for reevaluation of their asthma management plan.

Contraindications

Hypersensitivity to salbutamol sulfate or any component of the formulation. History of hypersensitivity reactions to other beta-agonists. Should not be used for prevention of threatened abortion. Contraindicated in patients with tachyarrhythmias and in those with known or suspected pheochromocytoma. Not recommended for patients experiencing acute myocardial infarction or severe cardiac arrhythmias.

Possible side effects

Common side effects (>1%): nervousness, headache, tremor, tachycardia, palpitations, muscle cramps, throat irritation, cough. Less common side effects: hypokalemia, paradoxical bronchospasm, dizziness, nausea, vomiting, restlessness, insomnia. Rare but serious side effects: angina pectoris, hypertension, hypotension, arrhythmias, allergic reactions including urticaria, angioedema, rash, bronchospasm.

Drug interaction

Concomitant use with other sympathomimetic agents may potentiate cardiovascular effects. Beta-blockers (especially non-selective) may antagonize bronchodilating effects and produce severe bronchospasm. Use with MAO inhibitors or tricyclic antidepressants may potentiate cardiovascular effects. May enhance hypokalemic effect of xanthine derivatives, steroids, diuretics. ECG changes and/or hypokalemia may be potentiated by potassium-depleting diuretics.

Missed dose

Asthalin is used as needed for symptom relief rather than on a fixed schedule. If a scheduled preventive dose is missed, take it as soon as remembered unless it is almost time for the next dose. Do not double the dose to make up for a missed one. For rescue use, administer when symptoms occur without regard to timing of previous doses, while respecting the maximum daily dosage limits.

Overdose

Overdosage may produce exaggeration of pharmacologic effects: angina pain, hypertension, hypokalemia, seizures, tachycardia with rates up to 200 beats per minute, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, malaise, and insomnia. Hypokalemia may occur following overdose. Treatment consists of discontinuation and supportive therapy. Cardioselective beta-blockers may be considered but with caution in patients with bronchospastic disease. Monitor cardiac status and serum potassium.

Storage

Store at room temperature between 15-30°C (59-86°F). Do not puncture or incinerate the container, even when empty. Keep away from direct sunlight, heat, and open flame. Do not freeze. Keep the cap on the mouthpiece when not in use. Clean the mouthpiece regularly with warm water and let it air dry completely before reassembly. Discard the inhaler when the counter reads “0” or after 3 months from removal from foil pouch, whichever comes first.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting or changing any medication regimen. Dosage and administration should be determined by a physician based on individual patient needs and medical history. Never disregard professional medical advice or delay seeking it because of something you have read in this product information.

Reviews

“Asthalin has been my emergency rescue medication for 15 years. Within minutes of administration, my breathing normalizes during acute attacks. The dose counter provides reassurance about remaining medication.” - Sarah K., asthma patient

“As an emergency physician, I rely on Asthalin for rapid bronchodilation in acute asthma presentations. Its predictable onset and efficacy make it indispensable in critical care settings.” - Dr. Michael Chen, MD

“After trying multiple bronchodilators, Asthalin provided the most consistent relief with minimal side effects. The portability allows me to maintain an active lifestyle without anxiety about sudden bronchospasm.” - James R., COPD patient

“Clinical studies consistently demonstrate Asthalin’s superior bronchodilatory effect compared to other SABAs. Its safety profile in pediatric populations makes it my first choice for young asthma patients.” - Dr. Elena Rodriguez, Pediatric Pulmonologist