Alesse is a combination oral contraceptive pill designed to provide effective pregnancy prevention through a balanced formulation of ethinyl estradiol and levonorgestrel. As a trusted monophasic option, it delivers a consistent hormone dose throughout the cycle, offering both contraceptive efficacy and cycle regularity. Approved by health authorities and widely prescribed, Alesse is recognized for its established safety profile and user-friendly dosing schedule. It represents a cornerstone in hormonal contraception, suitable for individuals seeking a reversible and highly reliable birth control method.

Features

• Contains 0.10 mg levonorgestrel and 0.02 mg ethinyl estradiol per active tablet
• Monophasic formulation ensuring uniform hormone delivery
• 21-day active pill regimen followed by a 7-day placebo interval
• Small, easy-to-swallow tablets with clear packaging for adherence
• Manufactured under strict pharmaceutical quality standards

Benefits

• Provides over 99% effective pregnancy prevention with perfect use
• Promotes regular, predictable menstrual cycles with often lighter and less painful periods
• May reduce the risk of ovarian cysts, ectopic pregnancy, and benign breast disease
• Non-contraceptive benefits include potential improvement in acne
• Offers reversible contraception, allowing for rapid return to fertility after discontinuation
• Enhances personal autonomy and family planning control

Common use

Alesse is primarily prescribed for the prevention of pregnancy. It may also be used in the management of moderate acne in females 15 years of age or older who have no known contraindications to hormonal contraception, have achieved menarche, and desire oral contraception. Some clinicians may recommend it off-label for menstrual cycle regulation in certain cases, though this should be evaluated on an individual basis.

Dosage and direction

Take one tablet daily by mouth at approximately the same time each day, for 21 consecutive days, followed by 7 days of placebo tablets or no tablets. Menstruation usually begins during the placebo week. Begin the next pack after the 7-day interval, regardless of whether bleeding has stopped. For first-time users, start on the first day of menstruation or the first Sunday after menstruation begins, as directed by a healthcare provider. Use a backup contraceptive method (e.g., condoms) for the first 7 days of the first cycle.

Precautions

• Not protective against HIV or other sexually transmitted infections
• Cigarette smoking increases the risk of serious cardiovascular side effects; this risk increases with age and heavy smoking (≥15 cigarettes/day)
• May influence glucose tolerance; monitor diabetic patients closely
• May increase blood pressure; regular monitoring advised
• Use with caution in patients with conditions that might be aggravated by fluid retention
• Periodic medical evaluations are recommended, including annual blood pressure check and routine breast/pelvic exams

Contraindications

• Thrombophlebitis, thromboembolic disorders, or history of these conditions
• Cerebrovascular or coronary artery disease
• Known or suspected carcinoma of the breast or estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Known or suspected pregnancy
• Liver dysfunction or disease
• Hypersensitivity to any component of Alesse

Possible side effects

Common side effects may include:

• Nausea
• Headache
• Breast tenderness
• Irregular bleeding or spotting
• Weight changes
• Mood changes

Serious (but less common) side effects may include:

• Blood clots
• Stroke
• Heart attack
• Liver tumors
• High blood pressure
• Gallbladder disease

Drug interaction

Alesse may interact with:

• Antibiotics (e.g., rifampin)
• Anticonvulsants (e.g., carbamazepine, phenytoin)
• Antifungals (e.g., griseofulvin)
• HIV medications (e.g., ritonavir)
• St. John’s Wort
• Certain seizure and tuberculosis medications

These agents may decrease the effectiveness of Alesse or increase the risk of breakthrough bleeding. Always inform your healthcare provider of all medications, supplements, and herbal products you are taking.

Missed dose

If one active pill is missed (24–48 hours late): Take it as soon as remembered, and take the next pill at the regular time. No backup contraception is needed.

If two active pills are missed in a row in the first two weeks: Take two pills on the day remembered and two pills the next day, then resume regular schedule. Use backup contraception for 7 days.

If two active pills are missed in the third week or three or more pills are missed anytime: Discard the pack and start a new pack on the same day. Use backup contraception for 7 days. Consider emergency contraception if unprotected intercourse occurred.

Overdose

Serious ill effects have not been reported following overdose of oral contraceptives. Overdose may cause nausea, vomiting, or withdrawal bleeding. In case of suspected overdose, seek medical attention or contact a Poison Control Center.

Storage

Store at room temperature (20–25°C or 68–77°F). Keep in the original blister pack, away from moisture, light, and children. Do not store in bathrooms or near sinks.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Do not disregard professional medical advice or delay in seeking it because of something you have read here.

Reviews

Alesse has been widely studied and prescribed for decades, with many users reporting high satisfaction due to its effectiveness and cycle-regulating benefits. Clinical trials and post-marketing surveillance support its safety and efficacy profile when used as directed. Individual experiences may vary; some users report side effects such as mood changes or breakthrough bleeding, which often subside after the first few cycles. Always discuss personal health history and concerns with a healthcare provider to determine if Alesse is appropriate for you.