Acticin Cream is a topical prescription medication containing permethrin 5% as its active ingredient. It is clinically proven to eradicate scabies mites and their eggs, as well as lice infestations, providing rapid relief from intense itching and skin irritation. This formulation is designed for precise application, offering a targeted approach to parasitic skin conditions with a well-established efficacy and safety profile. Medical professionals frequently recommend Acticin due to its high success rates and patient tolerance.

Features

• Contains 5% permethrin, a synthetic pyrethroid with potent parasiticidal activity
• Cream-based formulation for easy, controlled application
• Effective against Sarcoptes scabiei mites and their eggs
• Also indicated for the treatment of head lice and pubic lice
• Single-use tubes available in 30g and 60g sizes
• Minimal systemic absorption when used as directed

Benefits

• Provides complete eradication of scabies mites and lice with a single application in most cases
• Rapidly alleviates severe itching and discomfort associated with infestations
• Prevents transmission of scabies to close contacts and household members
• Reduces risk of secondary bacterial infections from scratching
• Simple, one-time treatment regimen enhances patient compliance
• Non-greasy, odorless formulation for comfortable use

Common use

Acticin Cream is primarily prescribed for the treatment of scabies, a contagious skin infestation caused by the Sarcoptes scabiei mite. It is also effectively used against infestations of head lice (Pediculus humanus capitis) and pubic lice (Pthirus pubis). The medication works by paralyzing and killing the parasites through disruption of their sodium channel function. Patients typically experience significant symptom relief within 24-48 hours of application, with complete resolution of symptoms within 2-4 weeks as the skin heals.

Dosage and direction

For scabies treatment: Thoroughly massage Acticin Cream into the skin from the neck to the soles of the feet, paying particular attention to creases and folds. Apply to clean, dry skin and leave on for 8-14 hours before washing off thoroughly with soap and water. A single application is usually sufficient. For lice treatment: Apply sufficient cream to cover hair and scalp, leave on for 10 minutes, then rinse thoroughly with water. Use a fine-toothed comb to remove dead lice and nits. Repeat application after 7 days if live lice are observed.

Precautions

• For external use only; avoid contact with eyes, nose, mouth, and mucous membranes
• Do not apply to broken or inflamed skin unless directed by a physician
• May cause temporary itching, burning, or tingling immediately after application
• Wash hands thoroughly after application unless treating hands for scabies
• Clothing, bedding, and towels should be washed in hot water and dried on high heat
• All household members and close contacts should be treated simultaneously to prevent reinfestation

Contraindications

• Known hypersensitivity to permethrin, pyrethroids, or chrysanthemums
• Patients with history of allergic reactions to topical scabicides or pediculicides
• Should not be used on infants under two months of age
• Contraindicated in patients with severe inflammatory skin conditions affecting large body surface areas

Possible side effects

Common side effects include temporary itching, burning, stinging, tingling, or numbness at the application site. Mild erythema or edema may occur. These symptoms typically resolve within a few days. Rare side effects may include rash, skin irritation, or allergic contact dermatitis. Systemic reactions are uncommon due to minimal absorption but may include headache, dizziness, or nausea in sensitive individuals.

Drug interaction

No significant drug interactions have been reported with topical permethrin applications. However, patients using other topical medications, especially those containing corticosteroids or other active ingredients, should consult their physician before simultaneous use. The cream base may theoretically affect the absorption of other topical products applied to the same area.

Missed dose

As Acticin is typically administered as a single application, missed dose scenarios are uncommon. If the application is washed off prematurely (before 8 hours for scabies treatment), reapply as soon as possible and maintain for the full recommended duration. For lice treatment requiring a second application, apply the missed dose as soon as remembered and continue with the recommended schedule.

Overdose

Topical overdose is unlikely due to minimal systemic absorption. Excessive application may increase the risk of local skin reactions including severe irritation, redness, or swelling. If accidentally ingested, seek immediate medical attention. Symptoms of oral ingestion may include nausea, vomiting, abdominal pain, and neurological symptoms such as dizziness or headache.

Storage

Store at room temperature between 15-30°C (59-86°F). Keep tube tightly closed when not in use. Do not freeze. Keep out of reach of children and pets. Discard any unused medication after treatment completion. Do not use beyond the expiration date printed on the packaging.

Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for diagnosis and treatment recommendations. Individual results may vary. Use only as directed by a physician. The manufacturer is not liable for any adverse effects resulting from improper use or self-diagnosis.

Reviews

Clinical studies demonstrate 85-95% efficacy rates for scabies eradication with single application of permethrin 5% cream. Dermatologists consistently rate Acticin as first-line therapy for scabies due to its excellent safety profile and high success rates. Patient satisfaction surveys indicate significant improvement in quality of life scores following treatment, with most reporting complete resolution of symptoms within four weeks. The formulation is particularly praised for its non-greasy texture and minimal odor compared to alternative treatments.